Molecular epidemiology of Crimean- Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran
| Autor: | Tahmasebi F, Sm, Ghiasi, Ehsan Mostafavi, Moradi M, Piazak N, Mozafari A, Haeri A, Ar, Fooks, Chinikar S |
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| Přispěvatelé: | Research and Science Branch, West Tehran Islamic Azad University [Tehran] (WTIAU), Department of Arboviruses and Viral Hemorrhagic Fevers [Tehran], Institut Pasteur d'Iran, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Entomology Laboratory, Parasitology Department, Iran University of Medical Science, Medical School, Shahid Beheshti Medical University, Veterinary Laboratory Agency, Veterinary laboratory Agency, This study was funded by the budget of the National Reference Labo- ratory for Arboviruses and Viral Haemorrhagic Fe- vers at Pasteur Institute of Iran |
| Rok vydání: | 2010 |
| Předmět: |
Male
Molecular Sequence Data RT-PCR MESH: Sheep Sheep Diseases Genome Viral Iran Ticks parasitic diseases CCHF MESH: CCHF MESH: Molecular Epidemiology Animals Humans MESH: Animals MESH: Phylogeny Phylogeny MESH: Ticks Molecular Epidemiology MESH: Molecular Sequence Data MESH: Humans Sheep MESH: Sheep Diseases MESH: Male MESH: Hemorrhagic Fever Virus Crimean-Congo MESH: RT-PCR MESH: Hemorrhagic Fever Crimean MESH: Arachnid Vectors [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology Hemorrhagic Fever Virus Crimean-Congo MESH: Iran Argas reflexus Arachnid Vectors Female Hemorrhagic Fever Crimean MESH: Genome Viral MESH: Argas reflexus MESH: Female |
| Zdroj: | University of Copenhagen Europe PubMed Central Journal of Vector Borne Diseases Journal of Vector Borne Diseases, Medknow Publications, 2010, 47 (4), pp.211-6 |
| ISSN: | 0972-9062 |
| Popis: | International audience; BACKGROUND & OBJECTIVES: Crimean-Congo hemorrhagic fever (CCHF) virus is a tick-borne member of the genus Nairovirus, family Bunyaviridae. CCHFV has been isolated from at least 31 different tick species. The virus is transmitted through the bite of an infected tick, or by direct contact with CCHFV-infected patients or the products of infected livestock. This study was undertaken to study the genetic relationship and distribution of CCHFV in the tick population of Hamadan province of Iran. METHOD: In this study, RT-PCR has been used for detection of the CCHFV genome. RESULTS: This genome was detected in 19.2% of the ticks collected from livestock of different regions of the Hamadan province in western Iran. The infected species belonged to Hyalomma detritum, H. anatolicum, Rhipicephalus sanguineus and Argas reflexus. With one exception, genetic analysis of the virus genome isolates showed high sequence identity to each other. Even though they clustered in the same group with the strain circulating in Iran, they had a closer relationship to the Matin strain. INTERPRETATION & CONCLUSION: Vector control programs should be applied for reducing population density of potential tick vectors in this province. Further surveys are indicated in this region to provide a better view of the distribution and epidemiology of the virus. |
| Databáze: | OpenAIRE |
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