A nanoporous gold membrane for sensing applications
| Autor: | Oo, S.Z., Silva, G., Carpignano, F., Noual, A., Pechstedt, K., Mateos, L., Grant-Jacob, J.A., Brocklesby, W.S., Horak, P., Charlton, M., Boden, S.A., Melvin, Tracy |
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| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Sensing and Bio-Sensing Research, Vol 7, Iss, Pp 133-140 (2016) Sensing and Bio-Sensing Research |
| ISSN: | 2214-1804 |
| DOI: | 10.1016/j.sbsr.2016.01.001 |
| Popis: | Design and fabrication of three-dimensionally structured, gold membranes containing hexagonally close-packed microcavities with nanopores in the base, are described. Our aim is to create a nanoporous structure with localized enhancement of the fluorescence or Raman scattering at, and in the nanopore when excited with light of approximately 600 nm, with a view to provide sensitive detection of biomolecules. A range of geometries of the nanopore integrated into hexagonally close-packed assemblies of gold micro-cavities was first evaluated theoretically. The optimal size and shape of the nanopore in a single microcavity were then considered to provide the highest localized plasmon enhancement (of fluorescence or Raman scattering) at the very center of the nanopore for a bioanalyte traversing through. The optimized design was established to be a 1200 nm diameter cavity of 600 nm depth with a 50 nm square nanopore with rounded corners in the base. A gold 3D-structured membrane containing these sized microcavities with the integrated nanopore was successfully fabricated and ‘proof of concept’ Raman scattering experiments are described. Graphical abstract Highlights • 3D structured gold microcavity membrane with a nanopore in the base designed • Theoretically for plasmon-enhanced detection • Fabrication of gold microcavity membrane with a nanopore • ‘Proof of concept’ study showing enhanced Raman scattering detection |
| Databáze: | OpenAIRE |
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