High resolution carotid black-blood 3T MR with parallel imaging and dedicated 4-channel surface coils
| Autor: | Saam, Tobias, Raya, Jose G, Cyran, Clemens C, Bochmann, Katja, Meimarakis, Georgios, Dietrich, Olaf, Clevert, Dirk A, Frey, Ute, Yuan, Chun, Hatsukami, Thomas S, Werf, Abe, Reiser, Maximilian F, Nikolaou, Konstantin |
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| Rok vydání: | 2009 |
| Předmět: |
Medicine(all)
Adult Carotid Artery Diseases Male lcsh:Diseases of the circulatory (Cardiovascular) system Ultrasonography Doppler Duplex Carotid Artery Common Research Reproducibility of Results Equipment Design Middle Aged Severity of Illness Index Young Adult lcsh:RC666-701 Predictive Value of Tests Case-Control Studies Image Interpretation Computer-Assisted Humans Female Carotid Artery Internal Magnetic Resonance Angiography Aged |
| Zdroj: | Journal of Cardiovascular Magnetic Resonance Journal of Cardiovascular Magnetic Resonance, Vol 11, Iss 1, p 41 (2009) |
| ISSN: | 1532-429X |
| Popis: | Background Most of the carotid plaque MR studies have been performed using black-blood protocols at 1.5 T without parallel imaging techniques. The purpose of this study was to evaluate a multi-sequence, black-blood MR protocol using parallel imaging and a dedicated 4-channel surface coil for vessel wall imaging of the carotid arteries at 3 T. Materials and methods 14 healthy volunteers and 14 patients with intimal thickening as proven by duplex ultrasound had their carotid arteries imaged at 3 T using a multi-sequence protocol (time-of-flight MR angiography, pre-contrast T1w-, PDw- and T2w sequences in the volunteers, additional post-contrast T1w- and dynamic contrast enhanced sequences in patients). To assess intrascan reproducibility, 10 volunteers were scanned twice within 2 weeks. Results Intrascan reproducibility for quantitative measurements of lumen, wall and outer wall areas was excellent with Intraclass Correlation Coefficients >0.98 and measurement errors of 1.5%, 4.5% and 1.9%, respectively. Patients had larger wall areas than volunteers in both common carotid and internal carotid arteries and smaller lumen areas in internal carotid arteries (p < 0.001). Positive correlations were found between wall area and cardiovascular risk factors such as age, hypertension, coronary heart disease and hypercholesterolemia (Spearman's r = 0.45-0.76, p < 0.05). No significant correlations were found between wall area and body mass index, gender, diabetes or a family history of cardiovascular disease. Conclusion The findings of this study indicate that high resolution carotid black-blood 3 T MR with parallel imaging is a fast, reproducible and robust method to assess carotid atherosclerotic plaque in vivo and this method is ready to be used in clinical practice. |
| Databáze: | OpenAIRE |
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