Lung function and symptoms in post-COVID-19 patients: a single-center experience
| Autor: | Nicola, Mumoli, Aldo, Bonaventura, Alessandra, Colombo, Alessandra, Vecchié, Marco, Cei, José, Vitale, Luca, Pavan, Antonino, Mazzone, Francesco, Dentali |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
chest CT scan
CVD cardiovascular disease Article PaO2 arterial partial pressure of oxygen PaCO2 arterial partial pressure of carbon dioxide V/Q ventilation/perfusion ratio ARDS acute respiratory distress syndrome IQR interquartile range COVID-19 coronavirus disease 2019 SARS-CoV-2 DOE dyspnea on exertion COVID-19 SpO2 peripheral capillary oxygen saturation respiratory tract diseases CT computed tomography PFT pulmonary function test hypocapnia GGO ground-glass opacity inflammation CRP C-reactive protein ABG arterial blood gas CPAP continuous positive airway pressure PaO2/FiO2 ratio of arterial partial pressure of oxygen to fractional inspired oxygen STROBE Strengthening the Reporting of Observational Studies in Epidemiology HRCT high-resolution computed tomography SD standard deviation SARS-CoV-2 severe acute respiratory syndrome coronavirus-2 |
| Zdroj: | Mayo Clinic Proceedings: Innovations, Quality & Outcomes |
| ISSN: | 2542-4548 |
| Popis: | Objective To address the lack of information about clinical sequelae of coronavirus disease 2019 (COVID-19). Patients and Methods Previously hospitalized COVID-19 patients who were attending the outpatient clinic for post-COVID-19 patients (ASST Ovest Milanese, Magenta, Italy) were included in this retrospective study. They underwent blood draw for complete blood count, C-reactive protein (CRP), ferritin, D-dimer, and arterial blood gas analysis (ABG) and chest high-resolution computed tomography (HRCT) scan. The primary endpoint was the assessment of blood gas exchanges after 3 months. Other endpoints included the assessment of symptoms and chest HRCT scan abnormalities and changes in inflammatory biomarkers after 3 months from hospital admission. Results Eighty-eight patients (men 73.9%) were included. Admission arterial ABG analysis showed hypoxia and hypocapnia and a PaO2/FiO2 of 271.4 (238-304.7) mmHg, that greatly improved after 3 months (426.19 [395.24-461.90] mmHg, P |
| Databáze: | OpenAIRE |
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