The Macrophages and Intestinal Symbiosis

Autor: Kloc, Malgorzata, Uosef, Ahmed, Elshawwaf, Mahmoud, Abdelshafy, Ahmed Adel Abbas, Elsaid, Kamal Mamdoh Kamal, Kubiak, Jacek Z, Ghobrial, Rafik Mark
Přispěvatelé: Houston Methodist Hospital [Houston, TX, USA], The University of Texas M.D. Anderson Cancer Center [Houston], Faculty of Medicine [ASU], Ain Shams University (ASU), Institut de Génétique et Développement de Rennes (IGDR), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Military Institute of Hygiene and Epidemiology (WIHE), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )
Rok vydání: 2020
Předmět:
Zdroj: Results and Problems in Cell Differentiation
Results and Problems in Cell Differentiation, Springer-verlag Berlin Heidelberg, 2020, 69, pp.605-616. ⟨10.1007/978-3-030-51849-3_23⟩
Results and Problems in Cell Differentiation, 2020, 69, pp.605-616. ⟨10.1007/978-3-030-51849-3_23⟩
ISSN: 0080-1844
DOI: 10.1007/978-3-030-51849-3_23⟩
Popis: International audience; The human intestinal tract is inhabited by trillions of microorganisms and houses the largest pool of macrophages in the human body. Being a part of the innate immune system, the macrophages, the professional phagocytes, vigorously respond to the microbial and dietary antigens present in the intestine. Because such a robust immune response poses the danger to the survival of the non-harmful and beneficial gut microbiota, the macrophages developed mechanisms of recognition and hyposensitivity toward the non-harmful/beneficial inhabitants of the gut. We will discuss the evolution and identity of some of these mechanisms in the following chapter.
Databáze: OpenAIRE
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