Prospective Assessment of the Diagnostic Accuracy of Instantaneous Wave-Free Ratio to Assess Coronary Stenosis Relevance: Results of ADVISE II International, Multicenter Study (ADenosine Vasodilator Independent Stenosis Evaluation II)
| Autor: | Escaned, J, Echavarria-Pinto, M, Garcia Garcia, Hector, van de Hoef, TP, de Vries, T (Ton), Kaul, P, Raveendran, G, Altman, JD, Kurz, HI, Brechtken, J, Tulli, M, Birgelen, C, Schneider, JE, Khashaba, AA, Jeremias, A, Baucum, J, Moreno, R, Meuwissen, M, Mishkel, G, van Geuns, Robert Jan, Levite, H, Lopez-Palop, R, Mayhew, M, Serruys, PWJC (Patrick), Samady, H, Piek, JJ, Lerman, A |
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| Přispěvatelé: | Cardiology, ACS - Amsterdam Cardiovascular Sciences, Faculty of Behavioural, Management and Social Sciences, Health Technology & Services Research |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Male
Cardiac Catheterization Adenosine Vasodilator Agents Hyperemia Coronary Angiography Severity of Illness Index Electrocardiography Predictive Value of Tests Humans Prospective Studies fractional flow reserve vasodilation Aged Coronary Stenosis Hemodynamics Reproducibility of Results Signal Processing Computer-Assisted Middle Aged instantaneous wave-free ratio Prognosis Fractional Flow Reserve Myocardial physiology Female coronary artery disease Algorithms |
| Zdroj: | JACC. Cardiovascular interventions, 8(6), 824-833. Elsevier Inc. JACC : cardiovascular interventions, 8(6), 824-833. Elsevier JACC-Cardiovascular interventions, 8(6), 824-833. Elsevier Inc. |
| ISSN: | 1876-7605 1936-8798 |
| Popis: | OBJECTIVES The purpose of this study was to assess the diagnostic accuracy of the instantaneous wave-free ratio (iFR) to characterize, outside of a pre-specified range of values, stenosis severity, as defined by fractional flow reserve (FFR) = 0.94) values was 91.6% (95% CI: 88.8% to 93.9%). When combined with FFR use within these cut-offs, the percent of stenoses properly classified by such a pre-specified hybrid iFR-FFR approach was 94.2% (95% CI: 92.2% to 95.8%). The hybrid iFR-FFR approach obviated vasodilators from 65.1% (95% CI: 61.1% to 68.9%) of patients and 69.1% (95% CI: 65.5% to 72.6%) of stenoses. CONCLUSIONS The ADVISE II study supports, on the basis rigorous methodology, the diagnostic value of iFR in establishing the functional significance of coronary stenoses, and highlights its complementariness with FFR when used in a hybrid iFR-FFR approach. (ADenosine Vasodilator Independent Stenosis Evaluation II-ADVISE II; NCT01740895) (C) 2015 by the American College of Cardiology Foundation. |
| Databáze: | OpenAIRE |
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