Cafeteria diet induce changes in blood flow that are more related with heat dissipation than energy accretion
Autor: | Sabater Martínez, David, Agnelli, Silvia, Arriarán, Sofía, Romero Romero, María del Mar, Fernández López, José Antonio, Alemany, Marià, 1946, Remesar Betlloch, Xavier |
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Přispěvatelé: | Universitat de Barcelona |
Rok vydání: | 2016 |
Předmět: |
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Anatomy and Physiology Metabolic Sciences lcsh:R Rats as laboratory animals lcsh:Medicine Circulation of the blood Hematology Tissue blood flow Diabetes and Endocrinology Lipids in human nutrition Cafeteria diet Rat Circulació sanguínia Rates (Animals de laboratori) Nutrition Lípids en la nutrició |
Zdroj: | Dipòsit Digital de la UB Universidad de Barcelona PeerJ PeerJ, Vol 4, p e2302 (2016) Recercat. Dipósit de la Recerca de Catalunya instname |
Popis: | Podeu consultar dades primàries associades a l'article a: http://hdl.handle.net/2445/96861 Background. A ``cafeteria'' diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to ``cafeteria'' diet. Rats were cannulated and fluorescent microspheres were used to determine blood flow. Results. Exposure to the cafeteria diet did not change cardiac output, but there was a marked shift in organ irrigation. Skin blood flow decreased to compensate increases in lungs and heart. Blood flow through adipose tissue tended to increase in relation to controls, but was considerably increased in brown adipose tissue (on a weight basis). Discussion. The results suggest that the cafeteria diet-induced changes were related to heat transfer and disposal. |
Databáze: | OpenAIRE |
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