A microbiological and clinical study of the safety and efficacy of baking-soda dentifrices
| Autor: | J J, Zambon, M L, Mather, Y, Gonzales |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Adolescent Carbonates Colony Count Microbial Dental Plaque Prevotella intermedia Streptococcus mutans Actinomyces Humans Microscopy Phase-Contrast Longitudinal Studies Dentifrices Ecosystem Aged Fusobacterium nucleatum Bacteria Dental Plaque Index Hydrogen Peroxide Middle Aged Gingivitis Drug Combinations Sodium Bicarbonate Microscopy Fluorescence Consumer Product Safety Tooth Discoloration Female Periodontal Index Safety Porphyromonas gingivalis Toothpastes Follow-Up Studies |
| Zdroj: | Compendium of continuing education in dentistry. (Jamesburg, N.J. : 1995). Supplement. 18(21) |
| Popis: | This article reports the results of a study that examined the clinical and microbiological changes associated with regular use of baking-soda dentifrices. Two dentifrice formulations were examined in a 6-month longitudinal study of 101 adult subjects with assessments for plaque, gingival inflammation, and stain at baseline and 3 and 6 months during the active phase of the study, and at 3 months after cessation of product use. One dentifrice contained 52% baking soda and 3% sodium percarbonate (ArmHammer PeroxiCare) while the other dentifrice contained 65% baking soda (ArmHammer Dental Care). Both dentifrices resulted in statistically significant reductions in dental plaque, gingival inflammation, and stain at all time periods compared to baseline. Dental plaque and buccal soft-tissue samples were obtained for microbiological analysis from a 50-subject subset. Microbiological assays, including bacterial culture, phase-contrast microscopy, and immunofluorescence microscopy, confirmed the safety of both formulations. Beneficial alterations in dental plaque bacteria were noted, including significant reductions in the levels of Actinomyces species. The data from this study indicate that dentifrices containing high levels of baking soda are clinically effective and microbiologically safe. |
| Databáze: | OpenAIRE |
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