Antimicrobial consumption and antimicrobial resistance: A snapshot of an Italian neuromuscular rehabilitation center

Autor: Barberi, G., Cola, Mc, Utri, P., Melardi, S., Alagna, B., Bramanti, P., Antonio Cascio
Přispěvatelé: Barberi, Giuseppina, De Cola, Maria Cristina, Dell'Utri, Pia, Melardi, Sara, Alagna, Bernardo, Bramanti, Placido, Cascio, Antonio
Předmět:
Zdroj: Università degli Studi di Palermo-IRIS
Popis: The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was assessed, including the incidence density of resistant isolates per 1000 patient-days (IDRI). Data on antimicrobial consumption, semi-annually, obtained from the hospital pharmacy, were expressed as Defined Daily Dose (DDD) per 1000 patient-days. The most frequently isolated microorganism was Klebsiella pneumoniae (19.3%), and a significant increase in piperacillin/tazobactam- resistant K. pneumoniae (p=0.04) was observed. Among all antimicrobials used, carbapenems were the most prescribed antibiotic class (31%).
Databáze: OpenAIRE