Autor:	Maciej Robert Krawczyński, Latos-Bieleńska A, Pecold K
Předmět:	Eye Neoplasms Retinoblastoma Humans Genetic Counseling Genes Retinoblastoma
Zdroj:	Europe PubMed Central
Popis:	The modern view for the mechanisms of retinoblastoma origination, based on the tumor suppressor genes theory, has been described in this work. The structure and function of the retinoblastoma gene and its protein product, with reference to the cell cycle, has been presented. On the ground of this data, possibilities of genetic molecular diagnostics and principles of competent genetic counselling have been described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9ec4c11773e8334fc03239321a339b1d http://europepmc.org/abstract/med/8072278 Zobrazit plný text záznamu