| Autor: |
Verder H, Agertoft L, Albertsen P, Nc, Christensen, Curstedt T, Ebbesen F, Gorm Greisen, Hobolth N, Holm V, Jacobsen T |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Europe PubMed Central |
| ISSN: |
0041-5782 |
| Popis: |
In this pilot study, Curosurf (200 mg/kg) was administrated to 34 patients with the respiratory distress syndrome in nasal-CPAP therapy with FiO2 requirements greater than 0.60 and/or TcPCO2 greater than 8 kPa. The surfactant was instilled during a short period of intubation or in a few cases via an intratracheal catheter (Ch. 6). The age of the patients on surfactant treatment ranged from two to 72 hours. Eighteen patients could be maintained on nasal-CPAP after treatment with Curosurf and only a few complications were seen in these infants. The other 16 patients subsequently required artificial ventilation and had a higher incidence of pulmonary and extrapulmonary complications. On the basis of these observations, we plan a randomized trial to investigate whether, administration of surfactant reduces the need for ventilator treatment and improves the odds for uneventful recovery in this category of patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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