Association of changes in mental health with weight loss during intensive lifestyle intervention: does the timing matter?
| Autor: | Alhalel, N., Schueller, S. M., O'Brien, M. J. |
|---|---|
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Obesity science & practice, vol 4, iss 2 Obesity Science & Practice |
| Popis: | Objective:This study examined changes in mental health symptoms and weight during weight loss treatment. It was hypothesized that worsening mental health would negatively impact weight loss. Methods:Data were analyzed from a trial of 92 Hispanic women with overweight/obesity and prediabetes, who were randomized to receive intensive lifestyle intervention (ILI), metformin 1,700mg daily, or standard care. Depression, anxiety and perceived stress were assessed at 0, 6 and 12months. Six- and 12-month weight change was compared among participants whose symptom scores worsened on any mental health measure (W) vs. improved or remained stable on all three (I/S). Results:Among ILI participants, the 12-month difference in weight loss between I/S and W groups was statistically significant: -5.1kg (P=0.001). From baseline to 6months, ILI participants in I/S and W groups experienced comparable weight loss. However, from 6 to 12months, W participants regained weight, whereas I/S participants experienced continued weight loss. In the metformin and standard care arms, there was no weight difference between I/S and W groups. Conclusions:In ILI, 12-month improvement or stability in mental health was significantly associated with weight loss. Weight trajectories between I/S and W groups diverged at 6months. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|