Risk Factors for High Mortality on the Liver Transplant Waiting List in Times of Organ Shortage: A Single-Center Analysis
| Autor: | Husen, Peri, Hornung, Julian, Benko, Tamas, Klein, Christian Georg, Willuweit, Katharina, Büchter, Matthias, Saner, Fuat, Paul, Andreas, Treckmann, Jürgen-Walter, Hoyer, Dieter Paul |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Original Paper Medizinische Fakultät » Universitätsklinikum Essen » Klinik für Allgemeinchirurgie Viszeral- und Transplantationschirurgie Time Factors Tissue and Organ Procurement Waiting Lists Adolescent Medizin Middle Aged Prognosis Liver Transplantation Medizinische Fakultät » Universitätsklinikum Essen » Klinik für Gastroenterologie und Hepatologie und Transplantationsmedizin End Stage Liver Disease Survival Rate Young Adult Risk Factors ddc:61 Humans Female ddc:610 Mortality Aged Retrospective Studies |
| Zdroj: | Annals of Transplantation |
| ISSN: | 2329-0358 1425-9524 |
| Popis: | BACKGROUND: Germany has the highest rate of patients dying or becoming unfit for transplant while waitlisted within the Eurotransplant region. Therefore, the aim of the current study was to analyze mortality as well as risk factors for mortality of candidates listed for liver transplantation at our center. MATERIAL AND METHODS: Between 01/2011 and 12/2013, 481 adult patients were listed for primary liver transplantation (LT) at a single German center. Clinical and laboratory parameters were prospectively collected and retrospectively analyzed by univariable and multivariable logistic regression and Cox proportional hazards. RESULTS: The mean model for end-stage liver disease (MELD) score of all liver transplant waitlist registrants (52.4 years, 60.1% male) was 16.9 (±10.2) at time of listing, with 10% of the listed patients having a MELD score of >32. After waitlisting, 133 (27.7%) candidates died within the follow-up period. Three-month-survival after listing for transplantation was 89% for patients ultimately receiving LT vs. 71.2% that did not receive LT (p |
| Databáze: | OpenAIRE |
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