[Treatment of mild malnutrition and reduction of morbidity in major abdominal surgery: randomized trial on 153 patients]
| Autor: | Pronio, Annamaria, DI FILIPPO, Annalisa Romina, Aguzzi, D, Laviano, Alessandro, Narilli, Piero, Piroli, S, Vestri, Anna Rita, Montesani, Chiara |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Aged 80 and over Male Digestive System Diseases Malnutrition Rome Nutritional Status Length of Stay Middle Aged Survival Analysis Female Urogenital Diseases Nutrition Assessment Postoperative Complications Treatment Outcome Male Urogenital Diseases Risk Factors Abdomen Preoperative Care Humans Female Prospective Studies Digestive System Surgical Procedures Aged |
| Zdroj: | La Clinica terapeutica. 159(1) |
| ISSN: | 0009-9074 |
| Popis: | Severe malnutrition (defined as weight loss more than 10% in a period of six months) is considered an important risk factor in major abdominal surgery, because of a higher post-operative mortality and morbidity. The aim of our study is to assess the role of mild malnutrition (weight loss low than 10% in a period of six months) as a risk factor in major abdominal surgery and to evaluate the efficacy of therapy in order to improve outcomes in terms of in-hospital mortality, length of hospital stay and post-operative complications. Moreover, we evaluated serum albuminemia and lymphocyte count, important nutritional index, as predictive risk factors.We performed a randomized prospective trial, and admitted in our institution 153 adult patients, 43 with mild malnutrition and 110 without. The malnourished patients were randomized in two groups: the first one received oral immunonutrition (Impact Oral) for 7-10 days before surgery (22 pz), the second one received no nutritional support.We observed a higher number of complications in the non-treated malnourished patients (57%) versus both the treated malnourished patients (13.6%) and the normal group (19%) (p0.001). Increased morbidity was observed in patients with serum albuminemia2.8 gr/dl (69.2%) and with lymphocyte count1.500 mm3 (57%).Nutritional enriched support demonstrated his efficacy in reducing morbidity, and length of hospital stay. Pre-operative oral immunonutrition might be suggested and established in all the patients with mild malnutrition that will be operated on major abdominal surgery. |
| Databáze: | OpenAIRE |
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