MicroRNAs-491-5p suppresses cell proliferation and invasion by inhibiting IGF2BP1 in non-small cell lung cancer

Autor: Gong, Fangchao, Ren, Ping, Zhang, Yan, Jiang, Jindong, Zhang, Hong
Rok vydání: 2015
Předmět:
Zdroj: Am J Transl Res
ISSN: 1943-8141
Popis: MicroRNAs-491-5p (miR-491-5p) has been found to involve in tumor initiation and development in several tumors. However, the biological function and underlying molecular mechanism of miR-491-5p in non-small lung cancer (NSCLC) remain unclear. This study was therefore to investigate biological role of and underlying molecular mechanisms of in NSCLC. It was found that miR-491-5p expression was significantly downregulated in NSCLC tissues when compared with corresponding adjacent normal tissues (P
Databáze: OpenAIRE