Thrombolysis in cervical artery dissection--data from the Cervical Artery Dissection and Ischaemic Stroke Patients (CADISP) database
| Autor: | Engelter, S. T., Dallongeville, J., Kloss, M., Metso, T. M., Leys, D., Brandt, T., Samson, Yves, Caso, V., Pezzini, A., Sessa, M., Beretta, S., Debette, S., Grond-Ginsbach, C., Metso, A. J., Thijs, V., Lamy, C., Medeiros, E., Martin, J. J., Bersano, A., Tatlisumak, T., Touzé, E., Lyrer, P. A., Renseigné, Non |
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| Přispěvatelé: | Equipe NEMESIS - Centre de Recherches de l'Institut du Cerveau et de la Moelle épinière (NEMESIS-CRICM), Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière (CRICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut cellule souche et cerveau (SBRI), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Engelter, S, Dallongeville, J, Kloss, M, Metso, T, Leys, D, Brandt, T, Samson, Y, Caso, V, Pezzini, A, Sessa, M, Beretta, S, Debette, S, Grond Ginsbach, C, Metso, A, Thijs, V, Lamy, C, Medeiros, E, Martin, J, Bersano, A, Tatlisumak, T, Touzé, E, Lyrer, P, Ferrarese, C, Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Service Parasitologie-Mycologie, Hôpital St. Antoine, Institut cellule souche et cerveau (U846 Inserm - UCBL1) |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Databases Factual Thrombolysi Carotid Artery Internal Dissection Cervical artery dissection Brain Ischemia Retrospective Studie Odds Ratio [INFO.INFO-IM]Computer Science [cs]/Medical Imaging Humans Multicenter Studies as Topic Thrombolytic Therapy cardiovascular diseases Ischaemic stroke Retrospective Studies Outcome Intracranial Hemorrhage Vertebral Artery Dissection Middle Aged Stroke Treatment Outcome Neurology Female Neurology (clinical) Intracranial Hemorrhages Complication Human |
| Zdroj: | European Journal of Neurology European Journal of Neurology, 2012, 19 (9), pp.1199-206. ⟨10.1111/j.1468-1331.2012.03704.x⟩ European Journal of Neurology, Wiley, 2012, 19 (9), pp.1199-206. ⟨10.1111/j.1468-1331.2012.03704.x⟩ |
| ISSN: | 1351-5101 1468-1331 |
| DOI: | 10.1111/j.1468-1331.2012.03704.x⟩ |
| Popis: | Objective: To examine whether thrombolysis for stroke attributable to cervical artery dissection (CeADStroke) affects outcome and major haemorrhage rates. Methods: We used a multicentre CeADStroke database to compare CeADStroke patients treated with and without thrombolysis. Main outcome measures were favourable 3-month outcome (modified Rankin Scale 0-2) and 'major haemorrhage' [any intracranial haemorrhage (ICH) and major extracranial haemorrhage]. Adjusted odds ratios [OR (95% confidence intervals)] were calculated on the whole database and on propensity-matched groups. Results: Among 616 CeADStroke patients, 68 (11.0%) received thrombolysis; which was used in 55 (81%) intravenously. Thrombolyzed patients had more severe strokes (median NIHSS score 16 vs. 3; P |
| Databáze: | OpenAIRE |
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