Accès à la préservation de la fertilité des adolescents et jeunes adultes de 15 à 24 ans atteints de cancers en Auvergne, France
| Autor: | Grèze, Victoria, Mechdoud, Sabrina, Vorilhon, Solène, Isfan, Florentina, Rouel, Nadège, Chaput, Laure, Brugnon, Florence, Kanold, Justyna |
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| Přispěvatelé: | CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand, Centre Hospitalier Universitaire de Clermont-Ferrand, Imagerie Moléculaire et Stratégies Théranostiques - Clermont Auvergne (IMoST), Université Clermont Auvergne (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Pédiatrie, Centre Hospitalier National Pédiatrique Charles de Gaulle (CHNP-CDG), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne (UCA), Centre d'Investigation Clinique [CHU Clermont-Ferrand] (CIC 1405), Institut National de la Santé et de la Recherche Médicale (INSERM)-Direction de la recherche clinique et de l’innovation [CHU Clermont-Ferrand] (DRCI), CHU Clermont-Ferrand-CHU Clermont-Ferrand, Imagerie Moléculaire et Stratégies Théranostiques (IMoST) |
| Jazyk: | francouzština |
| Rok vydání: | 2019 |
| Předmět: |
Cryopreservation
Male Adolescent [SDV]Life Sciences [q-bio] Ovary Fertility Preservation [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology [SDV.CAN]Life Sciences [q-bio]/Cancer Spermatozoa Adolescents and young adults Préservation fertilité Young Adult Sex Factors Adolescents et jeunes adultes Oocytes Humans Female France Cancer Retrospective Studies |
| Zdroj: | Bulletin du Cancer Bulletin du Cancer, John Libbey Eurotext, 2020, ⟨10.1016/j.bulcan.2020.03.013⟩ Bulletin du Cancer, John Libbey Eurotext, 2020, 107 (7-8), pp.773-778. ⟨10.1016/j.bulcan.2020.03.013⟩ |
| ISSN: | 1769-6917 0007-4551 |
| Popis: | Cancers of adolescents and young adults have particular epidemiological specificities. The improvement in their survival should be accompanied by an increased consideration of the treatments' side effects, among which the potential decrease in fertility. The objective of the study was to describe the access to fertility preservation of these patients at the University Hospital of Clermont-Ferrand over a period of 3 years.During this retrospective descriptive study, various socio-demographic and clinical data were collected.One hundred and fifty new cases of cancers were diagnosed in patients aged 15 to 24 years. Forty-four percent received at least one fertility consultation, 29 % for girls and 58 % for boys (P0.001). The number of cases that did not result in fertility preservation was significantly higher for girls than boys (P=0.005). Fertility preservation was mainly achieved by cryopreservation of ovarian tissue in female adolescents, ovocytes in young women and sperm in boys.We observed sex disparities in access to fertility preservation. Despite the existence of recommendations, progress remains to be made. The establishment of clinico-biological platforms should allow a better awareness of patients and professionals, and thus promote access to fertility preservation techniques for young patients with cancer. |
| Databáze: | OpenAIRE |
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