Biomarkers of intake for tropical fruits

Autor: Vázquez-Manjarrez, N., Ulaszewska, M., Garcia-Aloy, M., Mattivi, F., Praticò, G., Dragsted, L. O., Manach, C.
Přispěvatelé: Unité de Nutrition Humaine (UNH), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Nutrition, Exercise and Sports [Copenhagen], Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), University of Copenhagen = Københavns Universitet (KU), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán - National Institute of Medical Science and Nutrition Salvador Zubiran [Mexico], Dipartimento Qualità Alimentare e Nutrizione, Centro Ricerca ed Innovazione-Fondazione Edmund Mach, Fondazione Edmund Mach - Functional genomics, Fondazione Edmund Mach - Edmund Mach Foundation [Italie] (FEM), Department of Nutrition, Food Sciences and Gastronomy, University of Barcelona, Research and Innovation Centre, Centre for Integrative Biology (CIBIO), University of Trento (CIBIO), University of Trento [Trento], Food Biomarkers Alliance (FoodBAll) national Research Councils INRA Danish Innovation Foundation 420300002BUniversity of Rome La Sapienza ('Borsa di studio per la frequenza di corsi o attivita di perfezionamento all'estero' erogata ai sensi della legge) 398/89Ministry of Economy and Competitiveness (MINECO Spain) PCIN-2014-133-MINECOGeneralitat de Catalunya's Agency AGAUR 2017SGR1566CIBERFES European Union (EU) Ministry of Education, Universities and Research (MIUR)2075, ANR-14-HDHL-0002,FOODBALL,The Food Biomarkers Alliance(2014), University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), University of Copenhagen = Københavns Universitet (UCPH)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Genes & Nutrition
Genes & Nutrition, 2020, 15 (1), ⟨10.1186/s12263-020-00670-4⟩
Vázquez-Manjarrez, N, Ulaszewska, M M, Garcia-Aloy, M, Mattivi, F, Praticò, G, Dragsted, L O & Manach, C 2020, ' Biomarkers of intake for tropical fruits ', Genes & Nutrition, vol. 15, 11 . https://doi.org/10.1186/s12263-020-00670-4
ISSN: 1555-8932
DOI: 10.1186/s12263-020-00670-4⟩
Popis: International audience; Consumption of fruit and vegetable is a key component of a healthy and sustainable diet. However, their accurate dietary assessment remains a challenge. Due to errors in self-reporting methods, the available dietary information is usually biased. Biomarkers of intake constitute objective tools to better reflect the usual or recent consumption of different foods, including fruits and vegetables. Partners of The Food Biomarker Alliance (FoodBall) Project have undertaken the task of reviewing the available literature on putative biomarkers of tropical fruit intake. The identified candidate biomarkers were subject to validation evaluation using eight biological and chemical criteria. This publication presents the current knowledge on intake biomarkers for 17 tropical fruits including banana, mango, and avocado as the most widely consumed ones. Candidate biomarkers were found only for banana, avocado, and watermelon. An array of banana-derived metabolites has been reported in human biofluids, among which 5-hydroxyindole-acetic acid, dopamine sulfate, methoxyeugenol glucuronide, salsolinol sulfate, 6-hydroxy-1-methyl-1,2,3,4-tetrahydro-beta-carboline-sulfate, and other catecholamine metabolites. Their validation is still at an early stage, with insufficient data on dose-response relationship. Perseitol and mannoheptulose have recently been reported as candidate biomarkers for avocado intake, while the amino acid citrulline has been associated with watermelon intake. Additionally, the examination of food composition data revealed some highly specific phytochemicals, which metabolites after absorption may be further studied as putative BFI for one or several tropical fruits. To make the field move forward, untargeted metabolomics, as a data-driven explorative approach, will have to be applied in both intervention and observational studies to discover putative BFIs, while their full validation and the establishment of dose-response calibration curves will require quantification methods at a later stage.
Databáze: OpenAIRE
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