Clinical use of BCG and its complications: a case series

Autor: Claudia Colomba, Raffaella, R., Gabriele, M., Guida Marascia, F., Abbott, M., Gizzi, A., Anastasia, A., Palermo, G., Manlio, T., Antonio Cascio
Přispěvatelé: Claudia Colomba, Raffaella Rubino, Gabriele Mantia, Federica Guida Marascia, Michelle Abbott, Andrea Gizzi, Antonio Anastasia, Gabriele Palermo, Manlio Tolomeo, Antonio Cascio
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Università degli Studi di Palermo-IRIS
Popis: Bacillus Calmette-Guérin (BCG), a live, attenuated strain of Mycobacterium bovis, is the essential constituent of the vaccine against tuberculosis and the gold-standard adjuvant treatment for urothelial cancer of the bladder. Being a live, attenuated strain with a potential pathogenic action, bacilli can cause several complications, both locally near the inoculation site and remotely through blood dissemination. BCG-related disease can represent a side effect of anti-TB vaccination in patient with congenital or acquired immunodeficiency or a complication of the therapeutic schedule in oncologic patients. Herein we report five cases of BCG-related disease which occurred at the Infectious Diseases Department of the University Hospital of Palermo during a five-year period from January 2014 to December 2019.
Databáze: OpenAIRE