| Autor: |
Tv, Bershova, M.I. Bakanov, La, Bokeriia, Vi, Serbin, Tn, Mamedova, Il, Mikhaĭlova |
| Rok vydání: |
1994 |
| Předmět: |
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| Zdroj: |
Europe PubMed Central |
| ISSN: |
0042-8809 |
| Popis: |
Regulation of intracellular calcium homeostasis by means of secondary mediators calmodulin and 4,5-inositol phosphates (products of phosphatidyl inositol hydrolysis) was studied in children with ectopic forms of arrhythmias. Alterations in the system calmodulin-Ca2+ and the activity of phosphoinosite metabolism correlated highly with clinical manifestations of the arrhythmias. The data obtained suggest that a number of molecular mechanisms and responsible for arrhythmias were realized in cell membranes and depended on a complex of intracellular messengers affected within various steps of the hormonal signal transmission. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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