The Correlation between Troponin and Ferritin Serum Levels in the Patients with Major Beta-Thalassemia
| Autor: | Iraj, Shahramian, Motahhare, Razzaghian, Abbas Ali, Ramazani, Ghasem Ali, Ahmadi, Noor Mohammad, Noori, Ali Reza, Rezaee |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | International Cardiovascular Research Journal, Vol 7, Iss 2, Pp 51-55 (2013) International Cardiovascular Research Journal |
| ISSN: | 2251-9149 2251-9130 |
| Popis: | Background: Thalassemia is a hereditary hemoglobinopathy whose most common complication is cardiac involvement which ends up in these patients’ death. Since troponin is a sensitive and specific marker for the detection of microinfarct, we studied the relationship between troponin and ferritin serum levels for early diagnosis of cardiac involvement in these patients. Materials and Methods: This case-control study was performed on 80 patients, including 40 patients with major thalassemia and normal echocardiography and 40 healthy volunteers ranging from 6 months to 16 years old. All the children were examined and the eligible children who were not infected with known heart disease, iron deficiency anemia, kidney disease, diabetes, fever, and systemic diseases were enrolled into the study after obtaining written informed consents from their parents. At 8:00 A.M. before breakfast, 5cc blood was drawn from these children. After collecting the samples, ferritin and troponin serum levels were evaluated using ELISA and electro- kymonolonsense methods, respectively. The gathered data were analyzed through the SPSS statistical software (v. 20) and T-test. Besides, P value |
| Databáze: | OpenAIRE |
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