Use of microRNA‐encoded peptides to improve agronomic traits

Autor: Ormancey, Mélanie, Guillotin, Bruno, San Clemente, Hélène, Thuleau, Patrice, Plaza, Serge, Combier, Jean‐Philippe
Přispěvatelé: Laboratoire de Recherche en Sciences Végétales (LRSV), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Peptides et petits ARN, Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), ANR-16-CE12-0018,biomiPEPs,Vers une compréhension globale des miPEPs(2016)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Plant Biotechnology Journal
Plant Biotechnology Journal, Wiley, 2021, 19 (9), pp.1687-1689. ⟨10.1111/pbi.13654⟩
ISSN: 1467-7644
1467-7652
DOI: 10.1111/pbi.13654⟩
Popis: International audience; MicroRNAs (miRNAs) are small regulatory RNA molecules (21–24 nt) regulating the expression of target genes at the post-transcriptional level, by cleaving their mRNA. Because these target genes are mainly regulatory genes, miRNAs are involved at the crossroads of several biological processes (Liu et al., 2018). miRNAs are transcribed as long primary transcripts (pri-miRNAs) (Xie et al., 2005). Recent findings revealed that plant pri-miRNAs encode regulatory peptides called miRNA-encoded peptides (miPEPs) (Lauressergues et al., 2015; Sharma et al., 2020). miPEPs specifically enhance the transcription of their pri-miRNA, leading to phenotypes consistent with the functions of their cognate miRNA. Only a few miPEPs have been found as useful tools in agronomy. Indeed, soybean miPEP172c was shown to increase nodulation, aiming for a better yield (Couzigou et al., 2016), and grapevine miPEP171d increased adventitious root formation (Chen et al., 2020). In both cases, the role of the corresponding miRNA was previously known. Here, we questioned whether it would be feasible to screen a whole set of miPEPs for a particular phenotype in Arabidopsis thaliana, and whether it was possible to transpose these data to plants of agronomic interest.
Databáze: OpenAIRE