Rates of adverse reactions to first and second doses of BCG vaccination: results of a large community trial in Brazilian schoolchildren

Autor:	Dourado I, Mh, Rios, Sm, Pereira, Ss, Cunha, My, Ichihara, Jc, Goes, Lc, Rodrigues, Ana Bierrenbach, Ml, Barreto
Rok vydání:	2003
Předmět:	Hypersensitivity Immediate Male Adolescent Dose-Response Relationship Drug Fever Prognosis Mass Vaccination Risk Assessment Cohort Studies Erythema Lymphadenitis Skin Ulcer BCG Vaccine Prevalence Humans Female Registries Child Students Tuberculosis Pulmonary Brazil Immunization Schedule
Zdroj:	Europe PubMed Central
ISSN:	1027-3719
Popis:	To evaluate the incidence of adverse reactions to first and second bacille Calmette-Guérin (BCG) vaccination in schoolchildren.Enhanced surveillance in a Brazilian trial. Suspected reactions were reported to a nurse who visited cases and completed a standard form.Among 71341 schoolchildren studied, 33 reactions were reported. Of these, 25 fulfilled the criteria, resulting in a rate of one per 2854 vaccinations, with no deaths or BCG-osis. Reactions to second doses were more common than to first BCG vaccinations, but this difference was not statistically significant.Adverse reactions to a second dose of BCG may be more frequent than reactions to a first dose, but they are still rare events.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8acb2a27baae5f1901dfe92e9583bb07 https://pubmed.ncbi.nlm.nih.gov/12729348 Zobrazit plný text záznamu