| Autor: |
Graziani R, Monti M, Sejdiu B, Gozzetti F, Martelli D, Tampieri E, Isola E, Zanchelli F, Briganti M, Cenacchi G, Fabbrizio B, Buscaroli A. |
| Přispěvatelé: |
Graziani R, Monti M, Sejdiu B, Gozzetti F, Martelli D, Tampieri E, Isola E, Zanchelli F, Briganti M, Cenacchi G, Fabbrizio B, Buscaroli A. |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. 36(4) |
| ISSN: |
1724-5990 |
| Popis: |
Lithium is a largely used and effective therapy in the treatment of bipolar disorder. Its toxic effects on kidneys are mostly diabetes insipidus, hyperchloremic metabolic acidosis and tubulointerstitial nephritis. Also, a correlation between lithium and minimal change disease has sometimes been described. We report here the case of a patient with severe bipolar disorder on lithium therapy who, without any pre-existing nephropathy, developed nephrotic syndrome and AKI with histopathologic findings pointing to minimal change disease. The patient was treated with symptomatic therapy; the discontinuation of lithium therapy resulted in the remission of AKI and of the nephrotic syndrome, thus suggesting a close relationship between lithium and minimal change disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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