PRGF® endoret injections for temporomandibular joint osteoarthritis treatment: a one-year follow-up
| Autor: | M, Giacomello, C, Mortellaro, C, Viganoni, A, Crimella, J, Fossati, D, Lauritano |
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| Přispěvatelé: | Giacomello, M, Mortellaro, C, Viganoni, C, Crimella, A, Fossati, J, Lauritano, D |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Temporomandibular Joint
Intra-Articular growth factor Temporomandibular Joint Disorder MED/28 - MALATTIE ODONTOSTOMATOLOGICHE Temporomandibular Joint Disorders Injections Follow-Up Studie Injections Intra-Articular osteoarthritis Plasma Economica Treatment Outcome growth factors Intercellular Signaling Peptides and Protein Humans Intercellular Signaling Peptides and Proteins Osteoarthriti platelet rich plasma Follow-Up Studies LS7_4 Human |
| Popis: | This clinical trial investigates the efficacy of PRGF-Endoret® injections for the treatment of temporomandibular joint osteoarthritis by providing patient evaluations at a one-year follow-up. Fifty-two patients with a diagnosis of osteoarthritis according to the American Society of Temporomandibular Joint Surgeons' guidelines underwent a cycle of 3 injections (1 per month) of platelet-derived growth factors (PRFG). Two clinical parameters, pain at rest and maximum non-assisted mouth opening, were assessed by the same blinded operator at the time of the diagnosis (baseline), at each appointment during the treatment and at a 1-year follow-up visit. Both the parameters showed improvements that were maintained over time. Statistical analyses evidenced significant changes within the first two injections. Data from the present investigation support findings from studies on other joints, which show the efficacy of PRGF-Endoret injections to reduce symptoms of osteoarthritis and to maintain improvements over time. |
| Databáze: | OpenAIRE |
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