Benzodiazepines in the acute management of seizures with autonomic manifestations: anticipate complications!
Autor: | Laurence, Lacroix, Joel, Fluss, Alain, Gervaix, Christian M, Korff |
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Jazyk: | angličtina |
Rok vydání: | 2011 |
Předmět: |
Male
Respiratory Insufficiency/complications/drug therapy Seizures/complications/drug therapy/physiopathology Hypoventilation/complications/drug therapy Diazepam ddc:618 Vomiting Hypoventilation Autonomic Nervous System Diseases/complications/drug therapy/physiopathology Lorazepam Hypertension/complications/drug therapy Benzodiazepines/adverse effects/therapeutic use Benzodiazepines Autonomic Nervous System Diseases Seizures Child Preschool Hypertension Diazepam/adverse effects/therapeutic use Humans Vomiting/complications/drug therapy Female Respiratory Insufficiency Child Lorazepam/adverse effects/therapeutic use |
Zdroj: | Epilepsia, Vol. 52, No 10 (2011) pp. e156-9 |
ISSN: | 0013-9580 |
Popis: | The use of rescue benzodiazepines in the management of seizures is widely accepted in emergency pediatric practice. They can, however, cause severe side effects, such as respiratory depression. We describe five patients who presented with severe respiratory depression following benzodiazepine administration for seizures with autonomic manifestations. We also discuss the relationship between the complications observed in our patients and the rescue treatment. A reduction in the dosage of benzodiazepines in the setting of epileptic patients with predominant autonomic symptoms may need to be considered. |
Databáze: | OpenAIRE |
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