Prolidase activity and oxidative stress in patients with major depressive disorder

Autor: Mh, Kokacya, Bahceci B, Bahceci I, Ar, Dilek, Recep Dokuyucu
Přispěvatelé: RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Bahçeci, Bülent, Bahçeci, İlkay, Dilek, Aziz Ramazan
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Psychiatria Danubina
Volume 26
Issue 4
Europe PubMed Central
Scopus-Elsevier
ISSN: 0353-5053
Popis: Dokuyucu, Recep/0000-0001-7881-8871 WOS: 000346149600003 PubMed: 25377365 Background: the aim of the current study was to determine whether the serum prolidase levels are associated with the etiopathogenesis of depression. Subjects and methods: This study included 29 patients with major depressive disorder (MDD), who were consecutively recruited from the psychiatric outpatient clinic, and 30 healthy individuals recruited from the general community. Each patient underwent a detailed diagnostic evaluation by two psychiatrists using the Structured Clinical Interview for DSM-IV (SCID-I). Serum prolidase activity and oxidative parameters were measured in the patient and control groups. the severity of depressive symptoms was assessed using the Hamilton Depression Rating Scale. Results: Serum prolidase level was significantly higher in patients with MDD compared to healthy subjects (p
Databáze: OpenAIRE