[Role of the non-enzymatic glycosylation of protein in the formation of human cataracts]

Autor:	SIMONELLI, Francesca, PENSA M, RINALDI E. RELATED ARTICLES, LINKS
Přispěvatelé:	Simonelli, Francesca, Pensa, M, RINALDI E., RELATED ARTICLES, Links
Rok vydání:	1989
Předmět:	Adult Aged 80 and over Male Aging Glycosylation genetic structures Lysine Middle Aged eye diseases Cataract Diabetes Mellitus Type 2 Humans Female sense organs Eye Proteins Schiff Bases Aged
Zdroj:	Bollettino della Societa italiana di biologia sperimentale. 65(4)
ISSN:	0037-8771
Popis:	We have measured the free epsilon amino groups in soluble and insoluble proteins of clear human lenses and diabetic and non-diabetic senile cataractous lenses. The free epsilon amino groups content of soluble and insoluble proteins was significantly lower in diabetic cataracts than in clear lenses and non diabetic senile cataracts. Our results seem to demonstrate that non-enzymatic glycosylation of lens protein could play a role in the pathogenesis of cataract in diabetes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::861986ebe6f29d8d60c4ddf1a1cc1a9f https://pubmed.ncbi.nlm.nih.gov/2505814 Zobrazit plný text záznamu