Regeneration potential of decellularized periodontal ligament cell sheets combined with 15-Deoxy-Δ

Autor: Yao, Jiang, Jia-Mei, Liu, Jia-Ping, Huang, Ke-Xi, Lu, Wei-Lian, Sun, Jing-Yi, Tan, Bo-Xiu, Li, Li-Li, Chen, Yan-Min, Wu
Rok vydání: 2021
Předmět:
Zdroj: Biomedical materials (Bristol, England).
ISSN: 1748-605X
Popis: Periodontitis is a chronic inflammatory disease characterized by loss of attachment and destruction of the periodontium. Decellularized sheet, as an advanced tissue regeneration engineering biomaterial, has been researched and applied in many fields, but its effects on periodontal regeneration remain unclear. In this study, the biological properties of decellularized human periodontal ligament cell (dHPDLC) sheets were evaluated in vitro. Polycaprolactone/gelatin (PCL/GE) nanofibers were fabricated as a carrier to enhance the mechanical strength of the dHPDLC sheet. 15-deoxy-[Formula: see text]-prostaglandin J
Databáze: OpenAIRE