Association between serum ferritin level, cardiac and hepatic T2-star MRI in patients with major β-thalassemia
| Autor: | Eghbali A, Taherahmadi H, Shahbazi M, Bahador Bagheri, Ebrahimi L |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Iranian Journal of Pediatric Hematology and Oncology Europe PubMed Central |
| ISSN: | 2228-6993 2008-8892 |
| Popis: | Background Frequent blood transfusion is often associated with iron overload. Proper use of iron chelators to treat iron overload requires an accurate measurement of iron levels. Magnetic resonance T2-star (T2* MRI) can measure iron level in the heart and liver. Our goal was to see whether an association exists between serum ferritin level and T2* MRI in patients with major beta thalassemia. Materials and Methods Sixty patients with a diagnosis of major beta thalassemia were enrolled in the study. They were older than five years old and needed regular transfusion. Cardiac and hepatic T2*MRI and mean serum ferritin levels were measured within 3 months. Results No significant correlation was observed between serum ferritin level and cardiac T2*MRI (p=0.361, r=-0.120).However, a significant correlation was observed between serum ferritin and liver T2*MRI (p=0.021, r=-0.297). Conclusion Our results showed an association between hepatic T2*MRI and serum ferritin level. |
| Databáze: | OpenAIRE |
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