Anatomical demonstration of a medullary enkephalinergic pathway potentially implicated in the oro-facial muscle atonia of paradoxical sleep in the cat

Autor:	Fort, P., Rampon, C., Gervasoni, D., Christelle Peyron, Luppi, P. H.
Rok vydání:	2001
Předmět:	Male Neurons Medulla Oblongata Reticular Formation Facial Muscles Sleep REM Enkephalins Immunohistochemistry Methionine Muscle Tonus Neural Pathways Cats Animals Female
Zdroj:	Scopus-Elsevier Europe PubMed Central ResearcherID
ISSN:	1096-214X
Popis:	The present study was aimed to compare in detail the distribution within the rostral ventromedial medulla of Methionin-Enkephalin-immunoreactive neurons with efferent projections to the facial or trigeminal motor nuclei, using a double immunostaining technique in colchicine-treated cats. Following cholera toxin B subunit injections in the facial or trigeminal motor nuclei, we found that respectively 55% and 65% of the medium to large-sized retrogradely labeled cells in the lateral part of the nucleus reticularis magnocellularis were Methionin-Enkephalin-positive. For both motor nuclei, the double-labeled neurons had similar morphology and size and were located exactly in the same area. They could therefore belong to the same population of reticular enkephalinergic neurons. Based on these and previous anatomical and electrophysiological data, we propose that these enkephalin-containing neurons could participate in the hyperpolarization of brainstem and spinal somatic motoneurons during paradoxical sleep.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7e919dfc542e3a1d2caff52268637d47 https://pubmed.ncbi.nlm.nih.gov/11382865 Zobrazit plný text záznamu