Effect of Flushing the Endometrial Cavity With Follicular Fluid on Implantation Rates in Sub-Fertile Women Undergoing Invitro Fertilization: A Randomized Clinical trial

Autor: Hamdi, Kobra, Nouri, Mohammad, Farzaneh, Sara, Mirza-Aghdazadeh-Attari, Mohammad, Naghavi-Behzad, Mohammad, Mohammadi, Sahar
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Family and Reproductive Health, Vol 12, Iss 4 (2019)
Journal of Family & Reproductive Health
Hamdi, K, Nouri, M, Farzaneh, S, Mirza-Aghdazadeh-Attari, M, Naghavi-Behzad, M & Mohammadi, S 2018, ' Effect of Flushing the Endometrial Cavity With Follicular Fluid on Implantation Rates in Sub-Fertile Women Undergoing Invitro Fertilization : A Randomized Clinical trial ', Journal of Family and Reproductive Health, vol. 12, no. 4, pp. 184-190 .
ISSN: 1735-9392
1735-8949
Popis: Objective: To examine the effectiveness of intrauterine injection of follicular fluid in in vitro fertilization (IVF). Materials and methods: A parallel randomized control clinical study was conducted on 110 patients attending Al-Zahra Educational-Medical Center of Tabriz University of Medical Sciences. Female candidates for IVF were categorized into intervention (n = 55) and control (n = 55) groups using Randlast software (version 1.2). Following an identical protocol of gonadotropin-releasing hormone (Gnrh) antagonist stimulating ovulation, in the intervention group a total of 2mL of follicular fluid was injected as intrauterine after the accomplishment of follicular puncture. Embryo transfer was carried out after 2-3 days. The rates of implantation, as well as chemical and clinical pregnancy were compared between the two groups. Results: There were no significant differences in chemically proven pregnancy (19 in intervention group (34.5%) vs. 23 (41.8%) in control group p = 0.43), or in clinical pregnancy (30.9% vs. 38.2%, respectively p = 0.42), and in implantation rates (11.52 ± 2.57 % (range, 0-66.7) vs 18.79 ± 3.72 % (range, 0-100), respectively). Conclusion: Injection of follicular fluid into the uterine cavity in candidates for IVF neither improves nor adversely affects the outcome of the therapy.
Databáze: OpenAIRE
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