[Atrial flutter: a possible early sign of acute rejection in heart transplantation. A case report]

Autor: Serge Boveda, Galinier M, Lagrange P, Lagrange A, Cérène A, Delay M, Baccar H, Defaye P, Jp, Bounhoure, Jm, Fauvel
Jazyk: francouzština
Rok vydání: 2001
Předmět:
Zdroj: Europe PubMed Central
ISSN: 0003-9683
Popis: The authors report the case of a cardiac transplant patient with a recurrence of atrial flutter two months after electrical cardioversion and despite long-term preventive treatment with amiodarone. Early investigation for signs of rejection with 4 endomyocardial biopsies was negative. Aggravation of the haemodynamic status due to flutter with a rapid ventricular response led to an attempted radio-frequency ablation. Endocavitary mapping confirmed persistence of sinus activity in the native atrium and the presence of a circuit of type I isthmic flutter (anticlockwise circuit) in the donor atrium. Ablation by radio-frequency in the same procedure was successful. A fifth myocardial biopsy the same day finally confirmed stage 3A acute rejection. No signs of recurrent rejection or arrhythmia have been observed after 24 months' follow-up in this patient. This preliminary experience confirms the need to look for graft rejection by repeated myocardial biopsies in cardiac transplant, patients with atrial flutter and the efficacy of radio-frequency ablation in cases of resistance to conventional therapy.
Databáze: OpenAIRE