| Autor: |
Guzel, Murat, Dogru, Mehmet Tolga, Simsek, Vedat, Demir, Vahit, Alp, Caglar, Kandemir, Huseyin, Yildirim, Nesligul, Kisa, Ucler |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
American journal of cardiovascular disease. 9(4) |
| ISSN: |
2160-200X |
| Popis: |
Background: Dipper and non-dipper hypertension are different clinical forms of essential hypertension. In this study, the effect of circadian blood pressure changes on serum SCUBE-1 and soluble CD40 ligand (sCD40L) levels was investigated in patients with hypertension. Methods: A total of 100 participants aged 23-89 years were included in the study. Patients with essential hypertension were followed up by ambulatory blood pressure measurement. Results: Serum SCUBE1 levels were significantly higher in the non-dipper group than in the normal group (P < 0.001). Dipper and non-dipper patients had significantly higher serum sCD40L levels when compared to the normal group (P = 0.048 and P = 0.035, respectively). We also found a positive correlation between SCUBE1, sCD40L levels and 24-hour mean systolic blood pressure levels (r: 0.232, p: 0.034 and r: 0.241, p: 0.027, respectively). Conclusion: Serum SCUBE1 and sCD40L levels were higher in hypertensive patients than normal participants. Serum SCUBE1 levels were higher in patients with non-dipper compared to other participants. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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