The influence of the different morphological changes on gastric mucosa on somatostatin cell number in antrum mucosa and serum somatostatin
| Autor: | Silvio Mihaljević, Miroslava Katičić, Željko Krznarić, Branko Dmitrović, Ivan Karner, Mario Štefanić, Ljerka Pinotić, Marina Samardžija, Mirta Benšić |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Collegium antropologicum Volume 35 Issue 1 |
| ISSN: | 0350-6134 1848-9486 |
| Popis: | The aim of our paper was to investigate the influence of the different morphological changes on gastric mucosa on somatostatin D-cell number in antral mucosa and serum Somatostatin. We analyzed according to Sydney classification to what extent the severity of gastritis affect the observed hormonal values. somatostatin D-cell number in antral mucosa and serum Somatostatin values were compared between three groups of patients ; mild, moderate and severe chronic gastritis. The average number of somatostatin cell in biopsy sample of antrum mucosa was 30.41 +/- 35.38 (N = 17) in the case of middle form, 18.69 +/- 26.65 (N = 56) in moderate and in severe case of chronic gastritis 5.23 +/- 5.93 (N = 7) cells in mm2 of mucosa. The level of somatostatin in the serum of middle form gastritis were 26.43 +/- 28.76, moderate 19.95 +/- 35.93 and severe 17.88 +/- 17.66 pg/mL. In order to determine the number of somatostatin cells in antrum mucosa and serum somatostatin with present morphological changes of mucosa, it might helpful to exclude the patients with non-ulcer dyspepsia, but with the higher risk of premalignant and malignant changes. |
| Databáze: | OpenAIRE |
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