Distinct impacts of heart rate and right atrial-pacing on left atrial mechanical activation and optimal AV delay in CRT
| Autor: | Kyriacou, Andreas, Rajkumar, Christopher A., Pabari, Punam A., Sohaib, S.M. Afzal, Willson, Keith, Peters, Nicholas S., Lim, Phang B., Kanagaratnam, Prapa, Hughes, Alun D., Mayet, Jamil, Whinnett, Zachary I., Francis, Darrel P. |
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| Přispěvatelé: | British Heart Foundation |
| Rok vydání: | 2018 |
| Předmět: |
Technology
Science & Technology Cardiac & Cardiovascular Systems ATRIOVENTRICULAR DELAY cardiac resynchronization therapy heart failure EXERCISE 1103 Clinical Sciences NONINVASIVE BLOOD-PRESSURE HEMODYNAMIC MEASURES Engineering INTERATRIAL CONDUCTION 0903 Biomedical Engineering Cardiovascular System & Hematology electrophysiology‐clinical REPRODUCIBILITY Devices cardiovascular system Cardiovascular System & Cardiology electrophysiology-clinical cardiovascular diseases OPTIMIZATION Life Sciences & Biomedicine Engineering Biomedical |
| Zdroj: | Pacing and Clinical Electrophysiology |
| Popis: | Background Controversy exists regarding how atrial activation mode and heart rate affect optimal atrioventricular (AV) delay in cardiac resynchronization therapy. We studied these questions using high‐reproducibility hemodynamic and echocardiographic measurements. Methods Twenty patients were hemodynamically optimized using noninvasive beat‐to‐beat blood pressure at rest (62 ± 11 beats/min), during exercise (80 ± 6 beats/min), and at three atrially paced rates: 5, 25, and 45 beats/min above rest, denoted as Apaced,r+5, Apaced,r+25, and Apaced,r+45, respectively. Left atrial myocardial motion and transmitral flow were timed echocardiographically. Results During atrial sensing, raising heart rate shortened optimal AV delay by 25 ± 6 ms (P |
| Databáze: | OpenAIRE |
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