[Effect of Polfos on the bleeding time. II. Changes in selected parameters of the blood coagulation system and fibrinolysis]

Autor:	Konopelko M, Malinowska B, Ewa Chabielska, Buczko W
Rok vydání:	1989
Předmět:	Male Insecticides Bleeding Time Fibrinolysis Chlorfenvinphos Animals Rats Inbred Strains Blood Coagulation Tests Blood Coagulation Rats
Zdroj:	Europe PubMed Central
ISSN:	0465-5893
Popis:	The influence of Polfos on some parameters of the coagulation system and fibrinolysis in rats was examined. The present results indicate that Polfos had no effect on the coagulation system and fibrinolysis in the initial phase of intoxication (2 hours). In the late phase of intoxication (24 hours) a decrease in the prothrombin index, shortening of thrombin time, increase in the fibrinogen level and prolongation of euglobulin lysis time were observed. The results demonstrate that the normalization of the bleeding time in the late phase of intoxication depended on activation of the coagulation system and inhibition of fibrinolysis activation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::79939d311a2a7019b5db26fbff7c778a https://pubmed.ncbi.nlm.nih.gov/2796732 Zobrazit plný text záznamu