Salso-bromo-iodine thermal water: a nonpharmacological alternative treatment for postnasal drip-related cough in children with upper respiratory tract infections
| Autor: | La Mantia, Ignazio, Ciprandi, G., Varricchio, A., Cupido, F., Andaloro, C. |
|---|---|
| Přispěvatelé: | La Mantia, Ignazio, Ciprandi, G., Varricchio, A., Cupido, F., Andaloro, C. |
| Rok vydání: | 2018 |
| Předmět: |
Cancer Research
Physiology Endocrinology Diabetes and Metabolism Immunology Pilot Projects Salso-bromo-iodine thermal water isotonic saline postnasal drip Endocrinology Physiology (medical) Immunology and Allergy Humans Single-Blind Method Hyaluronic Acid Child Respiratory Tract Infections Plant Extracts postnasal drip Oncology Salso-bromo-iodine thermal water Diabetes and Metabolism Nasal Mucosa Cough Seeds Quality of Life isotonic saline Saline Solution Citrus paradisi Iodine |
| Zdroj: | Journal of biological regulators and homeostatic agents. 32(1 Suppl. 2) |
| ISSN: | 0393-974X |
| Popis: | Postnasal drip (PND)-related cough is a very common symptom in patients with upper respiratory tract infections (URTis). At present, there is not a standard treatment for postnasal drip and postnasal drip-related cough. The aim of this pilot study was to evaluate the efficacy of a specific salso-bromoiodine thermal water containing hyaluronic acid and grapefruit seed extract (SBI-H-GSE) comparing it with a normal saline solution in children with URTis who refer PND-related symptoms. The study was randomized, single-blind, and controlled. Study group (75 children) was treated with SBI-HGSE and control group (65 children) was treated with a normal saline solution; both compounds were administered by nasal nebulization With Rinowash nasal douche twice/day for 10 days a month for 3 consecutive months. Parent Cough-Specific Quality of Life questionnaire (PC-QOL) average score, the prevalence of symptoms and signs related to post-nasal drip, nasal mucociliary transport time (NMTT), duration and number of URTI episodes, antibiotic usage and days of absence from school were evaluated at baseline and after treatment. SBI-H-GSE therapy shows better and statistically significant trend after treatment when compared to control group for PC-QOL average score (p=0.011), NMTT (p=0.047), symptoms and signs related to post-nasal drip (all p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|