Reference values of cardiac volumes, dimensions, and new functional parameters by MR. a multicenter, multivendor study
| Autor: | Giovanni Donato, Aquaro, Giovanni, Camastra, Lorenzo, Monti, Massimo, Lombardi, Alessia, Pepe, Silvia, Castelletti, Viviana, Maestrini, Giancarlo, Todiere, Piergiorgio, Masci, Gabriella, di Giovine, Andrea, Barison, Santo, Dellegrottaglie, Martina, Perazzolo Marra, Gianluca, Pontone, Gianluca, Di Bella |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Adolescent Cardiac Volume Heart Ventricles cardiac magnetic resonance imaging Magnetic Resonance Imaging Cine left ventricular global function index longitudinal shortening reference values RV/LV EDV ratio sphericity index Age Factors Female Heart Humans Middle Aged Reference Values Sex Factors Young Adult nuclear medicine and imaging Radiology Nuclear Medicine and Imaging radiology Magnetic Resonance Imaging Cine |
| Popis: | To define reference values of cardiac volumes, dimensions, and new morpho-functional parameters normalized for age, gender, and body surface area by cine-bSSFP (balanced steady-state free-precession) magnetic resonance (MR).We enrolled 308 healthy subjects subdivided by gender and by six age classes: class I,15-20 years; class II,20-30 years; class III,30-40 years; class IV,40-50 years; class V,50-60 years; and class VI60 years. Dimensional, volumetric and morpho-functional parameters of the left (LV) and right (RV) ventricles were measured using cine-bSSFP MRI at 1.5T.The LV and RV end-diastolic volume indexes (EDVi) were inversely related to age (P0.0001 r = -0.34 and P0.0001 r = -0.37, respectively). In addition, the LV mass index decreased with age (P = 0.0004, r = -0.21). The LV longitudinal shortening was not significantly different among groups: ≥15% in all populations (95% confidence interval [CI]: 16-31). The sphericity index measured in end-diastole was higher in females than in males (P0.03): the upper limit was 40% for males and 42% for females. The normality cutoff of LV global function index was ≥33% in males and ≥35% in females. The end-diastolic volume (EDV) of RV and LV was balanced (RV/LV ratio 0.85-1.15) without differences in the population. The LV EDV/mass was 1.0-1.8 in males and 1.0-2.1 in females.This study provides potential age- and gender-specific reference.2 J. Magn. Reson. Imaging 2017;45:1055-1067. |
| Databáze: | OpenAIRE |
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