Low field magnetic resonance imaging of the equine distal interphalangeal joint: Comparison between weight-bearing and non-weight-bearing conditions
| Autor: | Evrard, Laurence, Audigié, Fabrice, Bertoni, Lélia, Jacquet, Sandrine, Denoix, Jean-Marie, Busoni, Valeria |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Imaging Techniques
Science Equines Research and Analysis Methods Diagnostic Radiology Random Allocation Skeletal Joints Diagnostic Medicine Forelimb Medicine and Health Sciences Animals Horses Musculoskeletal System Skeleton Phalanges Mammals Radiology and Imaging Organisms Biology and Life Sciences Eukaryota Magnetic Resonance Imaging Biological Tissue Cartilage Connective Tissue Body Limbs Vertebrates Amniotes Medicine Joints Anatomy Research Article Articular Cartilage |
| Zdroj: | PLoS ONE PLoS ONE, Vol 14, Iss 1, p e0211101 (2019) |
| ISSN: | 1932-6203 |
| Popis: | This descriptive study aimed to compare the magnetic resonance appearance of the distal interphalangeal joint articular cartilage between standing weight-bearing and non-weight-bearing conditions. Ten forefeet of live horses were scanned in a standing low-field magnetic resonance system (0.27 T). After euthanasia for reasons unrelated to the study, the non-weight-bearing isolated feet were scanned in a vertical positioning reproducing limb orientation in live horses. The same acquisition settings as during the weight-bearing examination were used. Thickness and cross-sectional area of the distal interphalangeal articular cartilage and joint space were measured on tridimensional T1-weighted gradient echo high resolution frontal and sagittal images at predetermined landmarks in both conditions and were compared using a linear mixed-effects model. Frontal images were randomized and submitted to 9 blinded readers with 3 different experience levels for identification of weight-bearing versus non-weight-bearing acquisitions based on cartilage appearance. Weight-bearing limbs had significantly thinner distal interphalangeal cartilage (p = 0.0001) than non-weight-bearing limbs. This change was greater in the distal phalanx cartilage than that of the middle phalanx. Blinded readers correctly identified 83% (range 65 to 95%) of the images as weight-bearing or non-weight-bearing acquisitions, with significantly different results observed among the different readers (p < 0.001) and groups (p < 0.001). These results indicate that distal interphalangeal articular cartilage and particularly cartilage of the distal phalanx thins when weight-bearing compared to the non-weight-bearing standing postmortem conditions and suggest that cartilage abnormalities may be more difficult to identify on weight-bearing standing magnetic resonance imaging. |
| Databáze: | OpenAIRE |
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