[Decision tools for selecting industrial sites where a systematic blood lead screening should be implemented]
| Autor: | Glorennec, Philippe, Ledrans, M., Fabres, B. |
|---|---|
| Přispěvatelé: | Groupe d'Etude de la Reproduction Chez l'Homme et les Mammiferes (GERHM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), ENSP Rennes |
| Jazyk: | francouzština |
| Rok vydání: | 2006 |
| Předmět: |
MESH: Humans
MESH: Child Preschool MESH: Environmental Exposure Infant Environmental Exposure MESH: Infant MESH: Lead Poisoning Lead Poisoning MESH: France Lead Child Preschool MESH: Child Humans Industry MESH: Industry [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie France Child MESH: Environmental Monitoring MESH: Lead Environmental Monitoring |
| Zdroj: | Epidemiology and Public Health / Revue d'Epidémiologie et de Santé Publique Epidemiology and Public Health / Revue d'Epidémiologie et de Santé Publique, Elsevier Masson, 2006, 54 (2), pp.117-25 Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique, 2006, 54 (2), pp.117-25 |
| ISSN: | 0398-7620 1773-0627 |
| Popis: | International audience; BACKGROUND: Children exposure to lead, even at low doses, can induce neurobehavioral and cognitive effects. In France, a consensus conference about lead poisoning in children has recently stated that exposure near an industrial site was a priority for blood lead screening. Selection criteria for industrial sites have therefore to be defined, especially because screening for lead poisoning requires a blood lead sample, that is an invasive procedure. METHODS: We propose here an operational procedure to select sites where systematic blood lead screenings have to be implemented. It is based on modeling blood lead levels of children aged 1-6 years. This is made by indirect dose estimation from environmental measurements, human exposure parameters and a dose/blood lead level relationship. Decision criteria are based on mean and extreme predicted blood lead level. The procedure is illustrated with a real life smelter case study. RESULTS: For the studied smelter, estimated blood lead levels are less than 100 microg(Pb)/l(blood) and therefore do not lead to recommend a systematic blood lead screening. CONCLUSIONS: Indirect dose estimation associated with blood lead level modeling is a useful tool for selecting where blood lead screenings have to be implemented around industrial sites. Possible improvements of the method are listed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect