Exploring the heterogeneity of human exposure to malaria vectors in an urban setting, Bouaké, Côte d’Ivoire, using an immuno-epidemiological biomarker

Autor: Traoré, Dipomin F., Sagna, André B., Adja, Akré M., Zoh, Dounin D., Adou, Kouassi A., Lingué, Kouassi N., Coulibaly, Issa, Tchiekoi, N’Cho Bertin, Assi, Serge B., Poinsignon, Anne, Dagnogo, Mamadou, Remoue, Franck
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Malaria Journal, Vol 18, Iss 1, Pp 1-10 (2019)
Malaria Journal
ISSN: 1475-2875
DOI: 10.1186/s12936-019-2696-z
Popis: Background In some African cities, urban malaria is a threat to the health and welfare of city dwellers. To improve the control of the disease, it is critical to identify neighbourhoods where the risk of malaria transmission is the highest. This study aims to evaluate the heterogeneity of malaria transmission risk in one city (Bouaké) in a West African country (Côte d’Ivoire) that presents several levels of urbanization. Methods Two cross-sectional studies were conducted in three neighbourhoods (Dar-es-Salam, Kennedy and N’gattakro) in Bouaké during both the rainy and dry seasons. Data on insecticide-treated net (ITN) use and blood samples were collected from children aged between 6 months and 15 years to determine the parasite density and the prevalence of Plasmodium falciparum and the level of IgG against the Anopheles gSG6-P1 salivary peptide, used as the biomarker of Anopheles bite exposure. Results The specific IgG levels to the gSG6-P1 salivary peptide in the rainy season were significantly higher compared to the dry season in all neighbourhoods studied (all p
Databáze: OpenAIRE
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