Sterolomics: State of the art, developments, limitations and challenges☆
| Autor: | Griffiths, William J., Wang, Yuqin |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Biochimica et Biophysica Acta |
| ISSN: | 1878-2434 0006-3002 |
| Popis: | Sterolomics can be thought of as the quantitative determination of the entire complement of molecules based on the cyclopentanoperhydrophenanthrene skeleton in a system. Mass spectrometry is the dominant analytical technology employed. In this article we highlight some pitfalls in analysis, data interpretation and annotation. We give our opinion on how some of these pitfalls can best be avoided. This article is part of a Special Issue entitled: BBALIP_Lipidomics Opinion Articles edited by Sepp Kohlwein. Highlights • Pitfalls in sterolomic analysis and data interpretation • Care needed to avoid ex vivo oxidation • Dangers with databases and purity of authentic standards |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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