The hypotensive response to des-Arg9-bradykinin increases during E. coli septicemia in the pig

Autor:	matthias siebeck, Et, Whalley, Hoffmann H, Weipert J, Fritz H
Rok vydání:	1989
Předmět:	Dose-Response Relationship Drug Reference Values Swine Sepsis Animals Blood Pressure Bradykinin Escherichia coli Infections
Zdroj:	Europe PubMed Central
ISSN:	0065-2598
Popis:	The sensitivity to des-Arg9-bradykinin of the cardiovascular system was largely increased in piglets with E. coli bacteremia. However, the sensitivity to bradykinin was unchanged under the same condition. These findings indicate the appearance of the kinin B1-receptor in the systemic circulation of the pig during septicemia. Bradykinin induced responses suggest a stable effect mediated by the classical B2-receptor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6a5b43f1141c8f4201c93444470fd0da https://pubmed.ncbi.nlm.nih.gov/2692415 Zobrazit plný text záznamu