Further evidence for the dispersion of the human fibrillar collagen genes

Autor:	cecile Jeanpierre, Mg, Mattei, Weil D, Kh, Grzeschik, Ml, Chu, Fo, Sangiorgi, Me, Sobel, Ramirez F, Junien C
Předmět:	Chromosome Mapping Nucleic Acid Hybridization DNA DNA Restriction Enzymes Hybrid Cells Chromosome Banding Mice Cricetulus Genes Cricetinae Karyotyping Animals Humans Collagen Procollagen Research Article
Zdroj:	Europe PubMed Central
Popis:	Recombinant DNA probes specific for the human pro alpha 1(II) and pro alpha 1(III) collagen chains have been used for the chromosomal localization of the two genes. Restriction endonuclease analysis of DNA from human-rodent hybrid cell lines in conjunction with in situ hybridization of human metaphasic chromosomes have shown that the gene coding for the pro alpha 1 chain of type II collagen (COL2A1) is located on chromosome 12 in the segment 12q131----12q132. Likewise, the gene coding for the pro alpha 1 chain of type III collagen (COL3A1) was assigned to the segment 2q31----2q323 of chromosome 2.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::69888b3b817aac891ac8f434e8892b37 http://europepmc.org/abstract/med/3004202 Zobrazit plný text záznamu