| Autor: |
Ma, Mahé, Mj, André, Moyon E, Le Mevel A, Soubeyran P, Hamidou M, Noel Milpied, Bourdin S, Jc, Cuillière, Jf, Chatal |
| Rok vydání: |
1997 |
| Předmět: |
|
| Zdroj: |
Europe PubMed Central |
| ISSN: |
0003-3995 |
| Popis: |
Chromosome aberrations were evaluated in the lymphocytes of 30 patients who had undergone radiotherapy several years before for non-Hodgkin's lymphoma. Twelve had received 20 Gy over the entire abdomen (group I), 12 wholebody irradiation at 1.5 Gy (group II) and 6 wholebody irradiation at 15 Gy (group III). Unirradiated patients seen for cytogenetic analysis during the same period served as controls. Overall results for the irradiated population were 13/27 (48%) evaluable patients with chromosome aberrations and 50/710 (7%) abnormal cells for a total of 73 aberrations (unstable: 35, stable: 38). The frequency of aberrations was statistically higher in group I (12% of cells) than in groups II (3.5%, p0.0001) and III (2.5%, p0.0002). Differences in irradiation dose and volume may account for the variations between groups. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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