The association between bisphenol a and polycystic ovarian syndrome: A case-control study

Autor:	Batool Hossein Rashidi, Massoud Amanlou, Tahere Behrouzi Lak, Mahya Ghazizadeh, Fedyeh Haghollahi, Maryam Bagheri, Bita Eslami
Předmět:	Adult lcsh:R5-920 Polycystic ovarian syndrome endocrine system diseases Case-control study Endocrine Disruptors Young Adult Bisphenol A Phenols Case-Control Studies Humans Female Genetic Predisposition to Disease HPLC Benzhydryl Compounds lcsh:Medicine (General) Polycystic Ovary Syndrome
Zdroj:	Scopus-Elsevier Acta Medica Iranica, Vol 55, Iss 12 (2018)
Popis:	Polycystic ovarian syndrome (PCOS) is an endocrine metabolic disorder with unclear etiopathogenesis among reproductive age women. Evidences show genetic susceptibility and environmental factors were associated with PCOS. The aim of this study was to find the association between urinary concentrations of Bisphenol-A as an endocrine disrupting chemical (EDC) and PCOS. A case-control study was conducted in 51 samples in each group. All cases were selected from women who diagnosed with PCOS at Gynecology and infertility center. The control group was selected from women who had clinical file in the center due to previous problem and came for routine check-up and pap smear. The participants were asked to collect a first-morning urine sample before any medical interventions. Total BPA in urine were measured with High Performance Liquid Chromatography (HPLC) method. Comparison of BPA level between two groups shows significantly higher level in PCOS group compared with control group (3.34 ± 2.63 vs 1.43 ± 1.57 ng/mL, P-value
Databáze:	OpenAIRE
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