Modalités pratiques de traitement des kératoses actiniques par photothérapie dynamique topique en lumière du jour avec l’aminolévulinate de méthyle
Autor: | Girard, Christian, Adamski, H., Basset-Séguin, N., Beaulieu, P., Dreno, B., Riboulet, J.-L., Lacour, J.-P. |
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Přispěvatelé: | Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Pathogénèse et contrôle des infections chroniques (PCCI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre Hospitalier Universitaire de Montpellier (CHU Montpellier ), Service de Dermatologie [Rennes] = Dermatology [Rennes], CHU Pontchaillou [Rennes], Service de Dermatologie [AP-HP Hôpital Saint-Louis], Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de dermatologie [Nantes], Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes), Service de Dermatologie [Nice], Hôpital Archet 2 [Nice] (CHU) |
Jazyk: | francouzština |
Rok vydání: | 2015 |
Předmět: |
Lumière du jour
Photosensitizing Agents Kératoses actiniques Skin Cream Pain Aminolevulinic Acid Photodynamic therapy Aminolévulinate de méthyle Keratosis Actinic Treatment Outcome Clinical Protocols Patient Education as Topic Photochemotherapy Scalp Dermatoses Sunlight Daylight Humans Actinic keratosis Methyl aminolevulinate [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology Facial Dermatoses Photothérapie dynamique topique |
Zdroj: | Annales de Dermatologie et de Vénéréologie Annales de Dermatologie et de Vénéréologie, Elsevier Masson, 2016, 143 (4), pp.257-263. ⟨10.1016/j.annder.2016.02.016⟩ |
ISSN: | 0151-9638 |
Popis: | International audience; Actinic keratosis (AK), also known as solar keratosis or pre-cancerous keratosis, is frequently observed in areas of skin exposed to sunlight, particularly in light-skinned patients. In France, photodynamic therapy using red light (conventional PDT) and methylamino 5-levulinate (MAL) is indicated in the treatment of thin or non-hyperkeratotic and non-pigmented multiple AK lesions or large zones covered with AK lesions. It is well-known for its efficacy but also for its side effects, especially pain during illumination, which can limit its use. An alternative to PDT using natural daylight has recently been proposed to treat actinic keratosis lesions, and results in greater flexibility as well as significant reduction in pain. The lesions are prepared as for conventional PDT, with MAL cream being applied by the physician or the patient, after which they are exposed to natural daylight for 2hours. The lesions are then gently cleansed and protected from natural light for 24hours. This paper seeks to provide a precise description of the daylight PDT procedure for the treatment of AK. |
Databáze: | OpenAIRE |
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