[Association of rs10912745 and rs4916375 polymorphisms located in the cluster of flavin-containing monooxygenase genes, with ischaemic cardioembolic stroke]

Autor:	Tv, Tupitsyna, Ea, Bondarenko, Petr Slominsky, Im, Shetova, Na, Shamalov, Timofeev DIu, Vi, Skvortsova, Sa, Limborskaia
Rok vydání:	2012
Předmět:	Stroke Cardiovascular Diseases Ischemia Risk Factors Multigene Family Oxygenases Humans Female Polymorphism Single Nucleotide Genetic Association Studies
Zdroj:	Europe PubMed Central
ISSN:	0016-6758
Popis:	Twenty-one SNPs located in the cluster of genes FMO1-FMO2-FMO3-FMO4 and adjacent areas were analyzed in the patients with ischaemic cardioembolic stroke and in the control group. Significant differences between these samples were found in the distribution of genotype and allele differences in two polymorphic loci, rs10912745 and rs4916375. It was shown that these polymorphic loci are associated with the risk of ischaemic cardioembolic stroke development.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::63989d85684c726de7ec696e4fe2ccf5 https://pubmed.ncbi.nlm.nih.gov/22830265 Zobrazit plný text záznamu