Identification of a Proanthocyanidin from Litchi Chinensis Sonn. Root with Anti-Tyrosinase and Antioxidant Activity
| Autor: | Saive, Matthew, Genva, Manon, Istasse, Thibaut, Frederich, Michel, Maes, Chloé, Fauconnier, Marie-Laure |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
anti-tyrosinase activity
Monophenol Monooxygenase Plant Extracts Communication Biphenyl Compounds lcsh:QR1-502 molecular identification Litchi chinensis Plant Roots Antioxidants Mass Spectrometry lcsh:Microbiology Litchi Picrates Fruit Spectroscopy Fourier Transform Infrared Oxidation-Reduction proanthocyanidins Chromatography High Pressure Liquid DPPH |
| Zdroj: | Biomolecules, Vol 10, Iss 1347, p 1347 (2020) Biomolecules |
| Popis: | This work follows an ethnobotanical study that took place in the island of Mayotte (France), which pointed out the potential properties of Litchi chinensis Sonn. roots when used to enhance skin health and appearance. Through in vitro testing of a crude methanolic extract, high anti-tyrosinase (skin whitening effect) and antioxidant activities (skin soothing effect) could be measured. HPLC successive bio-guided fractionation steps allowed the purification of one of the compounds responsible for the biological activities. The isolated compound was characterized by UV, IR, MS and 2D-NMR, revealing, for the first time in Litchi chinensis Sonn. roots, an A-type proanthocyanidin and thus revealing a consensus among the traditional use shown by the ethnobotanical study, in vitro biological activities and chemical characterization. |
| Databáze: | OpenAIRE |
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